Lecture #5:  Animal Structure and Function

I.  INTRODUCTORY REMARKS ABOUT CELLS, TISSUES, ORGANS, AND ORGANISMS

1.  As multicellular organisms evolved, their bodies developed (thru trial and error) a variety of systems that allowed cells to metabolize and survive as a conglomerate.

2.  In the course of this increasing complexity, cells joined into groups (tissues) that had common structure and function. (tissue = "weave")

3.  different tissues became organized into specialized centers of function called organs, such as the stomach, heart, brain, etc.

4.  Several related organs can cooperate as an organ system such as the digestive, circulatory, and nervous systems.

5.  The various efforts of all the different organ systems of an organism must be combined and coordinated for the animal to survive, and the bulk of this coordination is carried out by the endocrine and nervous systems.

 

II.  TYPES OF ANIMAL TISSUES

A.  EPITHELIAL TISSUES

1.  Covers outside of the body and lines organs and cavities. (Fig 40.1)

2.  Simple epithelium (single layer) versus stratified epithelium (multiple tiers).

3.  Cells at surface may be cuboidal (dice), columnar (bricks), or squamous (tiles).

4.  Epithelial tissues are usually attached to a basement membrane, or basel lamina.

5.  Cells are closely joined, sometimes by tight junctions.

6.  This tight packing protects against mechanical injury, microbes, and fluid loss.

7.  Epithelial layers called mucous membranes secrete a slimy solution that lubricates a surface and keeps it moist (e.g., the GI tract and respiratory system).

8.  Some mucous membranes have beating cilia (e.g., oviducts and respiratory tubes).

B.  CONNECTIVE TISSUES

1.  This type tissue has sparse cells scattered through an extracellular matrix.

2.  The non-living matrix generally consists of a web of fibers embedded in a homogenous ground substance that may be liquid, jelly-like, or solid.

3.  Types of connective tissue: (Fig. 40.2)

a.  "Loose" connective tissue (the most common) is based on three kinds of fibers:

(1)  collagenous fibers (most abundant protein in animal kingdom).

(2)  elastic fibers (made of protein) have a resilience that complements collagen.

(3)  reticular fibers join connective tissue to adjacent tissues. (in loose connective tissue, the cells are mainly fibroblasts and macrophages.)

b.  Fibrous connective tissue is "dense" due to high concn of collagen fibers. (Fig. 40.2)

c.  Cartilage has collagen fibers in a rubbery ground substance called chondrin. (Fig. 40.2)

d.  Bone is based on a collagen matrix deposited by osteoblasts along with calcium phosphate that hardens into hydroxyapatite. (Haversian systems) (Fig. 40.2)

e.  Adipose tissue is a specialized form of loose connective tissue that stores fat in a single large fat droplet in the adipose cells. (Fig. 40.2)

f.  Blood is an extraspecialized form of loose connective tissue imbedded in a fluid matrix called plasma. (red cells, white cells, and platelets) (Fig. 40.2)


C.  TYPES OF VERTEBRATE MUSCLE  (skeletal, cardiac, and smooth) (Fig 40.4)

1.  Muscle consists of elongated excitable cells capable of contraction.

2.  Muscle tissue is the most abundant tissue in most mammals (to allow motility).

a.  skeletal muscle is responsible for voluntary movement (striated).

b.  smooth (visceral) muscle is responsible for involuntary movements of organisms. (i.e., GI tract, bladder, arteries, and other internal organs)

c.  cardiac muscle is sort of a mixture, with intercalated discs that fuse the branching cardiac cells into a syncytium. (it has intrinsic rhythmicity)

 

III.  THE INTERNAL VERSUS THE EXTERNAL ENVIRONMENT

1.  Body size and shape have certain limits (e.g. whales versus protazoans).

2.  Life involves a constant interaction between the external environment and the internal environment of the organism. (Fig. 40.8)

3.  The digestive, respiratory, circulatory, and excretory systems all have specialized exchange surfaces to help achieve the needs of the internal environment from the external environment.

4.  In simplest terms, organisms must maintain a constant internal environment--in essence a constant physical (temperature, osmolarity, etc) and chemical (pH, electrolytes, glucose, etc) environment for every cell.

 

IV.  REGULATING THE INTERNAL ENVIRONMENT

1.  Vertebrate cells are bathed in an "interstitial fluid". the function of the vertebrate organ systems is to maintain the consistency of this interstitial fluid.

2.  The French physiologist Claude Bernard called this constant internal environment, "le milieu interior".

3.  The maintenance of this internal environment, or interstitial fluid, in a steady state is known as homeostasis. Thus, one might say that the organ systems of the body function to maintain homeostasis, i.e., a steady state.

 

V.  THE CONCEPT OF NEGATIVE FEEDBACK MECHANISMS

1.  Most homeostatic mechanisms (i.e., control mechanisms) in animals operate on the principle of negative feedback. (Fig 40.9a)

2.  This refers to biological mechanisms that function to "negate" disturbances (usually arising from the external environment) that alter the steady state of interstitial fluid in the internal environment of organisms.

3.  The control of body temperature at a constant level, as an example of negative feedback mechanisms.  (Fig 40.9b)

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