Biology 3449: Endocrinology: 2007 (Dr. Espey, CLS-216)

Lecture Syllabus

DATE TOPIC CHAPTER

Aug 23 . . . Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1

Aug 28 . . . Introduction (continued) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1

Aug 30 . . . The Vertebrate Endocrine System. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2

Sep 04 . . . The Mechanism of Hormone Action -- Hormone Receptors . . . . . . . . . . . . 3

Sep 06 . . . The Mechanism of Hormone Action -- Signal Transduction, Part I . . . . . . 3

Sep 11 . . . The Mechanism of Hormone Action -- Signal Transduction, Part II . . . . . . 3

Sep 13 . . . Hypophyseal (pituitary) Hormones . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5

Sep 18 . . . Hypophyseal Hormones, Part II . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5

Sep 20 . . . The Endocrine Hypothalamus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .6

Sep 25 . . . The Neurohypophyseal Hormones . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .7

Sep 27 . . . To Be Determined

Oct 02 . . . EXAM I (25%) (Tuesday: 2:10-4:00 PM)

Oct 04 . . . Hormonal Control of Calcium Homeostasis . . . . . . . . . . . . . . . . . . . . . . . . .9

Oct 09 . . . Pancreatic Hormones and Metabolic Regulation . . . . . . . . . . . . . . . . . . . . . 11

Oct 11 . . . Growth Hormones and Growth Factors . . . . . . . . . . . . . . . . . . . . . . . . . . . 12

Oct 12 . . . MID-SEMESTER RECESS

Oct 16 . . . Thyroid Hormones and Thyroid Hormone Regulation . . . . . . . . . . . . . . . .13

Oct 18 . . . Neurohormones, Catecholamines, and the Pineal Gland . . . . . . . . . . .7/14/20

Oct 23 . . . Lab work with rats (See schedule for your time slot)

Oct 25 . . . Steroid Hormone Metabolism . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15

Oct 30 . . . EXAM II (20%) (Tuesday: 2:10-4:00 PM)

Nov 01 . . . Work on Term Papers

Nov 06 . . . 30 minute quiz on LH action and ovulation presented by Dr. Espey (10:00 AM)

Nov 08 . . . Endocrinology of Sex Differentiation . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16

Nov 13 . . . Hormones of the Male Reproductive System . . . . . . . . . . . . . . . . . . . . . . .17

Nov 15 . . . Hormones of the Female Reproductive System . . . . . . . . . . . . . . . . . . . . . 18

Nov 20 . . . Endocrinology of Pregnancy and Contraception . . . . . . . . . . . . . . . . . . . . 19

Nov 22 . . . THANKSGIVING HOLIDAY

Nov 27 . . . Semester Reports

Nov 29 . . . Semester Reports

Dec 04 . . . No Class

Dec 06 . . . READING DAY

Dec 08 . . . FINAL EXAM (20%) (Saturday: 2:00-4:30 PM) (comprehensive???)

NOTE: The HONOR CODE is in effect for this course. All Endocrinology Students are expected to carry out homework assignments without assistance (directly, or indirectly) from other students.

NOTE: Normally, the only excuses for missing an exam are an illness that requires the attention of a physician, or a death in the family. Otherwise, be sure to clear with me any absence.

e-Mail: lespey@trinity.edu Website: www.trinity.edu/lespey

Biology 3449: Endocrinology 2007

Laboratory Syllabus

DATE TOPIC LOCATION

Aug 28 . . . No Lab Session

Sep 04 . . . Laboratory Methods in Endocrinology (Chapter #4) (3% of grade) . . . . CLS #128

Sep 11 . . . Signal Transduction and Other Membrane Phenomena . . . . . . . . . . . . . . . CLS #128

Sep 18 . . . Releasing Hormones: Guillemin vs Schally (Handout) (3% of grade) . . .CLS #128

Sep 25 . . . Library Science: UTHSC Medical Library, Room 2C (2% of grade) . . . UTHSCSA

Oct 02 . . . LECTURE EXAM I . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . CLS #128

Oct 09 . . . Statistical Analysis of Endocrinological Data (2% of grade) . . . . . . . . . . CLS #128

Oct 12 . . . MID-SEMESTER RECESS

Oct 16 . . . The Physiology of Ovarian Gene Expression & Ovulation (5% of grade). CLS #128

Oct 23 . . . Hormone Action on Rat Ovaries (See schedule for your time slot). . . . . . . CLS #135

Oct 30 . . . LECTURE EXAM II . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . CLS #128

Nov 06 . . . Free to work on Semester Reports

Nov 13 . . . Radioimmunoassay of Prostaglandin E₂ and Progesterone . . . . . . . . . . . CLS #135

Nov 20 . . . Gamma-Counter Operation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . CLS #242

Nov 22 . . . THANKSGIVING HOLIDAY

Nov 27 . . . Semester Oral Reports (10% of grade) . . . . . . . . . . . . . . . . . . . . . . . . . . . CLS #128

Dec 04 . . . No Class!

Dec 04 . . . RIA Reports Due Place in Espey ‘door-box’ CLS 216 (10% of grade)

NOTE: You should turn in an outline of your course schedule for all of your classes, along with a schedule of any other obligations you may have during a typical week, by October 16. This schedule is necessary to organize the Radioimmunoassay experiments that begin October 23.

NOTE: Oral presentations of your library research paper at the end of the semester will be limited to 20 minutes. A 2-3 page, typed summary of your report (including references to the literature) should be submitted on the day of your presentation. Also, note that students will be grading one another on their oral presentations (in order to gain experience with grading), but these grades will not be used by Dr. Espey to determine the grade for each student's presentation.

NOTE: Do not forget that all Endocrinology Students are expected to carry out homework assignments without assistance (directly, or indirectly) from other students.