Epithelia: functional modifications

10/14/99


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Table of Contents

Epithelia: functional modifications

Epithelia: archtype

The Polarized Epithelium

Epithelium to Lumen: apical modification

Striated Border, Brush Border, Cilia: diagrammatic view

Microvilli: diagrammatic view

Microvilli: cross-section

Microvilli with Glycocalyx and Actin Filaments

Microvillus: detail

Apical Microvilli

Cross-section Through Microvilli and Cilia

Cilium: diagrammatic, cross-section, longitudinal section

Cilium: detail

Intestinal Epithelia: what do you see?

Junctional Complexes: TEM view

The Whole Landscape of Epithelial Interactions

Junctional Adhesions: Cell to Cell Contact - 4 types

Tight Junction: zonula occludens

Tight Junction: the occluding junction

Tight Junction: a model

Sealing Strands: freeze fracture

Epithelial Transcellular Transport

Vectorial Transfer of Nutrients

The Reality of Tight Junctions

The Occluding Junction Function

Some Terminology

Anchoring Junctions

Anchoring Junction: schematic

Anchoring Junction: another view

Adhering Junctions: zonula adherens

Adherens Junction

The Cadherin Molecule: Ca++ - dependent cell-cell adhesion

Macula Adherens: spot desmosome

Desmosomes: idealized

Desmosome: a model

Nonjunctional Adhesions: Cell to Cell - 4 types

Integrins: transmembrane heterodimers

Cell to Matrix Adhesions

Focal Contact

Inside to Outside Linkage: actin to fibronectin

Focal Contact: a model

Hemidesmosome

Hemidesmosome: a model

Hemidesmosome: detail

Gap Junction: communicating junction

Gap Junction: a model

Gap Junctions: three views

Gap Junctions: cross-section through a field

Basement Membrane

Basement Membrane: functions

Basement Membrane, Basal Lamina

Basement Membrane Types

Protein Underlayment for Basement Membrane: 4 kinds

Laminin

Type IV Collagen: substrate for basement membranes

Keratinization

Epithelial Tumors

References

Author: Robert Blystone

Email: rblyston@Trinity.edu

Home Page: http://www.trinity.edu/rblyston

Other information:
This material is copyrighted. Please note the references for the images. This material produced for the Spring 1999 Biology 3431 course.

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