This course investigates the structure-function relationships of cellular machinery involved in gene expression and its roles in regulation across multiple levels of biological organization in prokaryotes and eukaryotes. Topics include structure and properties of nucleic acids/genomes and amino acids/proteins, nucleic acid polymerases, ribosomes and the variety of regulatory mechanisms governing the expression of genetic information. The course emphasizes an examination of experimental evidence that shapes our understanding of molecular biological phenomena. Laboratory experiments and projects illustrate key concepts and principles. Prequisite: BIOL 3450, 3458, 3466, or CHEM 3330
4 credits
Upper Division