| 2015-2021 | Danny J. Anderson, Ph.D. |
| 2010-2015 | Dennis A. Ahlburg, Ph.D. |
| 1999-2010 | John R. Brazil, Ph.D. |
| 1979-1999 | Ronald K. Calgaard, Ph.D. |
| 1976-1979 | Marion Bruce Thomas, Ph.D.* |
| 1970-1976 | Duncan Wimpress, Ph.D. |
| 1951-1970 | James Woodin Laurie, M.A., D.D. |
| 1950-1951 | Marion Bruce Thomas, Ph.D |
| 1942-1950 | Monroe D. Everett, D.D. |
| 1937-1942 | Frank L. Wear, D.D. |
| 1934-1937 | Raymond Hotchkiss Leach, Ph.D. |
| 1933-1934 | Samuel Lee Hornbeak, Ph.D., L.L.D.** |
| 1921-1933 | John Harmon Burma, D.D. |
| 1907-1921 | Samuel Lee Hornbeak, Ph.D., L.L.D. |
| 1904-1906 | Archelaus Ewing Turner, SC.D., L.L.D. |
| 1902-1904 | Leonidas C. Kirkes, A.M. |
| 1901-1902 | Jesse Anderson, Ph.D. |
| 1896-1900 | Luther Apelles Johnson, A.M.** |
| 1890-1896 | B. D. Cockrill, A.M. |
| 1889-1890 | Lunsford Dickens, Ph.D. |
| 1885-1889 | Luther Apelles Johnson, A.M. |
| 1883-1885 | Benjamin G. McLeskey, D.D. |
| 1882-1883 | S. T. Anderson, Ph.D.* |
| 1877-1878 | R. W. Pitman, M.A., D.D.* |
| 1869-1882 | William E. Beeson, D.D. |
* acting president
** former president, chairman of faculty during interim